18 February, 2011 Vo...
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通过花瓣采集插件采集于2012-03-26 09:12:46
18 February, 2011 Volume 41, Issue 4
On the cover: ERdj5 is the recently discovered protein disulfide reductase that accelerates ER-associated degradation (ERAD) of misfolded proteins. The film-like frames in the cover image depict the sequential ERAD eve
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The cover picture shows the concept of disulfide-constrained miniproteins as alternatives to antibodies for the development of new chemical entities. Their structural characteristics and beneficial pharmacokinetic profile highlight this peptide format for
About the cover : Nature Reviews Cancer 'Tumourgeddon' by Simon Bradbrook, inspired by this month's Focus issue.
About the cover : Nature Genetics April 2012 Volume 44 No 4 DNA Pendant by Alexander Davis (http://www.rowandavis.com/)
山东博科生物参展2012迪拜实验展 Arablab,山东博科生物 biobase Arablab 中东(迪拜)生化分析仪器、实验室装备、分析检测设备及教学仪器博览会-来宝网
24 September, 2010 Volume 39, Issue 6 On the cover: During mitosis, chromatin is condensed and transcription is generally turned off. In this issue, Kelly et al. (pp. 901–911) show that +1 nucleosomes located after transcriptional start sites during G0/G1
21 January, 2011 Volume 41, Issue 2 On the cover: The histone H4 mRNA coding region recruits the ribosome for its translation. In this issue, Martin et al. (pp. 197–209) identified two structural RNA elements, both located in the coding region of the hist
18 February, 2011 Volume 41, Issue 4 On the cover: ERdj5 is the recently discovered protein disulfide reductase that accelerates ER-associated degradation (ERAD) of misfolded proteins. The film-like frames in the cover image depict the sequential ERAD eve
4 March, 2011 Volume 41, Issue 5 On the cover: RNF20-dependent histone H2B ubiquitination required for transcription. In this issue, we identified RNF20-mediated H2B ubiquitination as an important factor for DNA double-strand break (DSB) repair. Ubiquitin
6 May, 2011 Volume 42, Issue 3 On the cover: Telomerase prevents telomere shortening and is required for the long-term proliferation of cancer cells. Telomerase inhibitors are currently in phase II clinical trials, but virtually nothing is known about how
4 November, 2011 Volume 44, Issue 3 On the cover: The cover depicts how the autophagy ubiquitin-like protein Atg8 is transferred from its E1, Atg7, to its E2, Atg3 (Taherbhoy et al., pp. 451–461). The two halves of the yin-yang represent the homodimeric A
9 December, 2011 Volume 44, Issue 5 On the cover: DNA-damage response is an important defense mechanism from genotoxic stress, and a critical component of the DNA-damage response is the p53 tumor suppressor. In this issue, Kim et al. (pp. 797–810) demonst
13 January, 2012 Volume 45, Issue 1 On the cover: RNA polymerase II elongation control is a highly utilized mechanism regulating transcription in metazoans. In this issue, Cheng et al. (pp. 38–50) demonstrate that Gdown1, a substoichiometric Pol II subuni
Cover art: Fabric of Life Series,Melitaea phoebe VMPR #1A4A141by John Arabolos University of New Haven, New Haven, onnecticut, USA (http://arabolosart.com)
About the cover : Nature Genetics January 2011 Volume 43 No 1 Copyright 2013 from The Molecules of Life by John Kuriyan, Boyana Konforti & David Wemmer. Reproduced by permission of Garland Science/Taylor & Francis LLC.
Cover art: http://bit.ly/sDqPde created by Daniel Kohn in Assembly Space with modular incidental music by Stanley Haskins (s.haskins@umiami.edu)
About the cover : Nature Genetics February 2012 Volume 44 No 2 Cover art: Coauthorship networks in the GWAS era (p113)
About the cover : Nature Biotechnology January 2012 Volume 30 No 1 Structural models of chromosomes in nuclei on background image of raw experimental data. Kalhor et al. describe advances in mapping chromosome contacts and representing the resulting dat
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